Conclusion Mirtazapine has diphasic action of anti-depression and-anxiety, its effect of anti-depression is equivalent to imipramine and that of anti-anxiety superior to imipramine, and has significant efficacy, higher safety and better compliance in depression associated with anxious symptoms. 结论米氮平具有抗抑郁抗焦虑双重作用,抗抑郁作用与丙米嗪相当,抗焦虑作用优于丙米嗪,治疗抑郁症伴焦虑症状疗效显著,安全性高、依从性好。